Reinitiated viral RNA-dependent RNA polymerase resumes replication at a reduced rate

Abstract

RNA-dependent RNA polymerases (RdRP) form an important class of enzymes that is responsible for genome replication and transcription in RNA viruses and involved in the regulation of RNA interference in plants and fungi. The RdRP kinetics have been extensively studied, but pausing, an important regulatory mechanism for RNA polymerases that has also been… (More)
DOI: 10.1093/nar/gkn836

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Cite this paper

@inproceedings{Vilfan2008ReinitiatedVR, title={Reinitiated viral RNA-dependent RNA polymerase resumes replication at a reduced rate}, author={Igor D. Vilfan and Andrea Candelli and Susanne Hage and Antti P. Aalto and Minna M. Poranen and Dennis Henry Bamford and Nynke H Dekker}, booktitle={Nucleic acids research}, year={2008} }