Reinforcing and discriminative stimulus effects of RTI 111, a 3-phenyltropane analog, in rhesus monkeys: interaction with methamphetamine

  title={Reinforcing and discriminative stimulus effects of RTI 111, a 3-phenyltropane analog, in rhesus monkeys: interaction with methamphetamine},
  author={Robert Ranaldi and Karen G. Anderson and F. Ivy Carroll and William L. Woolverton},
Abstract. Rationale: The neuronal actions of methamphetamine (MA) include an increase in extracellular levels of monoamines, presumably via reverse transport involving the monoamine transporters. This action is thought to play an important role in the effects of MA. Therefore, in the present experiment, it was hypothesized that a monoamine uptake blocker would block behavioral effects of MA related to its abuse. Objective: RTI 111, a newly synthesized 3-phenyltropane analog with high affinity… 
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  • M. Weed, W. Woolverton
  • Biology, Psychology
    The Journal of pharmacology and experimental therapeutics
  • 1995
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