Reinforcement of injectable calcium phosphate cement by gelatinized starches.

  title={Reinforcement of injectable calcium phosphate cement by gelatinized starches.},
  author={Huiling Liu and Ying Guan and Donglei Wei and Chunxia Gao and Huilin Yang and Lei Yang},
  journal={Journal of biomedical materials research. Part B, Applied biomaterials},
  volume={104 3},
  • Huiling LiuYing Guan Lei Yang
  • Published 1 April 2016
  • Materials Science, Medicine
  • Journal of biomedical materials research. Part B, Applied biomaterials
Current injectable calcium phosphate bone cements (CPC) encounter the problems of low strength, high brittleness, and low cohesion in aqueous environment, which greatly hinder their clinical applications for loading-bearing bone substitution and minimally invasive orthopedic surgeries. Here, a strategy of using gelatinized starches to reinforce injectable CPC was investigated. Four types of starches, namely corn starch, crosslinked starch, cationic starch, and Ca-modified starch, were studied… 

Pregelatinized starch as a cohesion promoter improves mechanical property and surgical performance of calcium phosphate bone cement: the effect of starch type

CPB modified by pregelatinised waxy maize starch (CPB-W) had the highest mechanical strength, longest setting time, and most compact structure compared with other CPBs.

Fabrication and Characterization of Injectable Calcium Phosphate-based Cements for Kyphoplasty

Calcium phosphate cements (CPCs) with high bioactivity and bio-degradability have great potential for orthopaedic applications. However, handling performance and mechanical properties of current CPCs

Strontium-calcium phosphate hybrid cement with enhanced osteogenic and angiogenic properties for vascularised bone regeneration.

A strontium-enhanced calcium phosphate hybrid cement (Sr-CPHC) was developed to improve both biological and physicochemical properties of CPC and showed great potential for clinical applications such as the repair of ischemic osteonecrosis and critical-size bone defects.

Physicochemical properties of bone marrow mesenchymal stem cells encapsulated in microcapsules combined with calcium phosphate cement and their ectopic bone formation

Results indicate that BMSCs encapsulated in ACA microcapsules combined with CPC composite scaffolds have good application prospects as bone tissue engineering materials.

A novel injectable calcium phosphate-based nanocomposite for the augmentation of cannulated pedicle-screw fixation

The promising results for the CPN clearly suggest its potential for replacing PMMA in the application of cannulated pedicle-screw fixation and its worth of further study and development for clinical uses.

Enhancing effects of radiopaque agent BaSO4 on mechanical and biocompatibility properties of injectable calcium phosphate composite cement.



Improvement of Anti-Washout Performance of Calcium Phosphate Cement Using Modified Starch

Calcium phosphate cements (CPCs) are well-known orthopedic materials for filling bone. However, CPC pastes tend to disintegrate immediately when contacting with blood or other aqueous (body) fluids,

Control of setting behavior of calcium phosphate paste using gelatinized starch

A new type of calcium phosphate (CP) paste that retains plasticity during kneading and sets promptly under a physiological condition was successfully prepared by mixing Ca4O(PO4)2 (TTCP) and CaHPO4

Influence of anti-washout agents on the rheological properties and injectability of a calcium phosphate cement.

This study provided a convenient way to use the injectable CPC with good anti-washout performance when the paste was exposed to blood, and also had potential prospects for the wider applications in surgery such as orthopaedics, oral, and maxillofacial surgery.

Fibre-reinforced calcium phosphate cements: a review.

  • C. CanalM. Ginebra
  • Materials Science
    Journal of the mechanical behavior of biomedical materials
  • 2011

Reinforcing of a calcium phosphate cement with hydroxyapatite crystals of various morphologies.

In vitro cell culture experiments showed that the developed biomaterial system is noncytotoxic and averaged elastic modulus and hardness values of the cements are consistent with those reported for trabecular and cortical human bones, indicating a good match of the micromechanical properties for their potential use for bone repair.

Effect of substitutional Sr ion on mechanical properties of calcium phosphate bone cement

A novel calcium phosphate cement was developed by adding different amount of SrO to tetracalcium phosphate during the fabrication process. The experimental results show that compressive strength of

Effects of fibre reinforcement on the mechanical properties of brushite cement.