Rehabilitation pharmacology: bridging laboratory work to clinical application.

  title={Rehabilitation pharmacology: bridging laboratory work to clinical application.},
  author={John P. Phillips and Deidre J. Devier and Dennis M. Feeney},
  journal={The Journal of head trauma rehabilitation},
  volume={18 4},
BACKGROUND Converging lines of evidence indicate the utility of medications for enhancing functional recovery after brain injury. METHODS Laboratory studies using rats and cats suggest that drugs augmenting noradrenergic function may facilitate recovery after cortical injury, when combined with appropriate environmental experience. This short-term noradrenergic strategy can be initiated months after injury and enhance recovery to a higher ultimate outcome level. Additional support for a… CONTINUE READING

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