Rehabilitating equipoise.

@article{Miller2003RehabilitatingE,
  title={Rehabilitating equipoise.},
  author={Paul B. Miller and Charles Weijer},
  journal={Kennedy Institute of Ethics journal},
  year={2003},
  volume={13 2},
  pages={93-118}
}
When may a physician legitimately offer enrollment in a randomized clinical trial (RCT) to her patient? Two answers to this question have had a profound impact on the research ethics literature. Equipoise, as originated by Charles Fried, which we term Fried's equipoise (FE), stipulates that a physician may offer trial enrollment to her patient only when the physician is genuinely uncertain as to the preferred treatment. Clinical equipoise (CE), originated by Benjamin Freedman, requires that… CONTINUE READING

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