Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer.

@article{Won2012RegulatoryRO,
  title={Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer.},
  author={Kyu Yeoun Won and S. Lim and Gou Young Kim and Youn Wha Kim and Sang-Ah Han and Jeong Yoon Song and Dong-ki Lee},
  journal={Human pathology},
  year={2012},
  volume={43 2},
  pages={221-8}
}
Cancer cells show a higher rate of anaerobic respiration than normal cells. The exact mechanisms for this higher glycolysis rate in cancer cells remain to be elucidated. The results of recent studies have indicated that p53, the most commonly mutated tumor suppressor gene, may have important functions in the regulation of energy-generating metabolic… CONTINUE READING