Regulatory role of excitatory amino acids in reproduction

  title={Regulatory role of excitatory amino acids in reproduction},
  author={Virendra B. Mahesh and Darrell W Brann},
Glutamate, the major excitatory amino acid (EAA) transmitter in the central nervous system, has been implicated as a critical mediator in brain function. Glutamate and its receptors are found in all key hypothalamic areas critically involved in reproduction. Administration of glutamate and its agonists can bring about LH release in animals with a steroid background. Antagonists of the ionotropic glutamate receptors inhibited LH release and abolished the steroid-induced and the preovulatory LH… CONTINUE READING
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Program of the 76th Annual Meeting of The Endocrine Society

  • D. W. Brann, K. Kumaresan, V. B. Mahesh
  • Abstract 449,
  • 1994
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