Regulatory properties of myocardial myosin.

  title={Regulatory properties of myocardial myosin.},
  author={C N Fenner and Dean Towle Mason and Robert Zelis and Joan Wikman-Coffelt},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={70 11},
The ATPase activity of purified myocardial myosin was activated by either K(+) or Ca(++); the addition of one in the presence of the other caused inhibition. According to Hill-plot analyses the K(+)-saturation curves were sigmoidal (n = 2.92), while the Ca(++)-saturation curves were hyperbolic (n = 1.25). Ca(++)-saturation curves in the presence of K… CONTINUE READING