Regulatory function of CpG-activated B cells in late-phase experimental allergic conjunctivitis.

PURPOSE To determine how CpG, an immunostimulatory sequence, affects experimental allergic conjunctivitis and to determine the mechanisms of its action. METHODS Experimental allergic conjunctivitis was induced in mice to investigate the suppressive mechanism of CpG treatment. Cytokine profiling, fluorescence-activated cell sorting analyses, and adoptive… CONTINUE READING