Regulatory elements of hepatitis B virus transcription.

@article{Moolla2002RegulatoryEO,
  title={Regulatory elements of hepatitis B virus transcription.},
  author={Naazneen Moolla and Michael Kew and Patrick Arbuthnot},
  journal={Journal of viral hepatitis},
  year={2002},
  volume={9 5},
  pages={323-31}
}
The precise modulation of hepatitis B virus (HBV) gene expression is essential for replication of the virus. HBV sequences are transcribed under the control of the preC/pregenomic, S1, S2 and X promoters. With the exception of S1, all the HBV promoters lack the orthodox TATA box motifs required for the formation of the transcription initiation complex, and as such they represent a unique model of transcription initiation elements. The presence of two enhancer sequences and negative regulatory… CONTINUE READING

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