Regulatory effects of sulfur dioxide on the development of atherosclerotic lesions and vascular hydrogen sulfide in atherosclerotic rats.

@article{Li2011RegulatoryEO,
  title={Regulatory effects of sulfur dioxide on the development of atherosclerotic lesions and vascular hydrogen sulfide in atherosclerotic rats.},
  author={Wei Li and Chaoshu Tang and Hongfang Jin and Junbao Du},
  journal={Atherosclerosis},
  year={2011},
  volume={215 2},
  pages={323-30}
}
OBJECTIVE This study was designed to examine the effect of sulfur dioxide (SO(2)) on atherosclerotic progression and endogenous vascular hydrogen sulfide (H(2)S) in rats with atherosclerosis (AS). METHODS Twenty-eight male rats were randomly divided into control, AS and AS+SO(2) groups. Rats were given a single dose of vitamin D(3) and fed a high-cholesterol diet for 8 weeks to induce AS. Plasma lipids, aortic ultrastructure, and atherosclerotic lesions were detected at the termination of… CONTINUE READING

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