Regulatory effects and molecular mechanism of Trigonostemon reidioides on lipopolysaccharide-induced inflammatory responses in RAW264.7 cells

  title={Regulatory effects and molecular mechanism of Trigonostemon reidioides on lipopolysaccharide-induced inflammatory responses in RAW264.7 cells},
  author={Ju Young Shin and Jae-Shin Kang and Hye-Woo Byun and Eun-Kyung Ahn},
  journal={Molecular Medicine Reports},
  pages={5137 - 5142}
Trigonostemon reidioides (Kurz) Craib has been traditionally used for the treatment of vomiting and asthma in Cambodia. However, the underlying molecular mechanisms of the anti-inflammatory effect of T. reidioides extract remains unknown. The present study investigated the anti-inflammatory activity and molecular action of an ethanol extract of T. reidioides (ETR) in lipopolysaccharide (LPS)-induced RAW264.7 macrophage cells. Nitric oxide assays, ELISA, reverse transcription-quantitative… Expand
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