Regulatory effect of the glial Golli-BG21 protein on the full-length murine small C-terminal domain phosphatase (SCP1, or Golli-interacting protein).

@article{JaramilloTatis2014RegulatoryEO,
  title={Regulatory effect of the glial Golli-BG21 protein on the full-length murine small C-terminal domain phosphatase (SCP1, or Golli-interacting protein).},
  author={Sergio Jaramillo-Tatis and Kenrick A. Vassall and Vladimir V. Bamm and George Harauz},
  journal={Biochemical and biophysical research communications},
  year={2014},
  volume={447 4},
  pages={
          633-7
        }
}

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References

SHOWING 1-10 OF 31 REFERENCES

Characterization of the Golli-interacting Protein and its interactions with BG21 and the 21.5-kDa isoform of Myelin Basic Protein

A novel protocol for the purification of a functional full-length GIP has been developed with a yield of 4-mg/L culture with 85% purity and an enzymological approach was used to study the GIPBG21 and GIP-MBP-21.5 interactions.

Identification of a protein that interacts with the golli‐myelin basic protein and with nuclear LIM interactor in the nervous system

The ability of GIP to interact with both golli and NLI, and the nuclear co‐localization of G IP and golli in many cells, indicates a role for the golli products of the MBP gene in NLI‐ associated regulation of gene expression.

The Effects of Threonine Phosphorylation on the Stability and Dynamics of the Central Molecular Switch Region of 18.5-kDa Myelin Basic Protein

The results support the hypothesis that the central conserved segment of MBP constitutes a molecular switch in which the conformation and/or intermolecular interactions are mediated by phosphorylation/dephosphorylation at T92 and T95.

Purification and spectroscopic characterization of the recombinant BG21 isoform of murine golli myelin basic protein

Like “classic” MBP and the Golli‐MBP isoform J37, rmBG21 is intrinsically disordered, implying multi functionality, and that its conformation depends on its environment and bound ligands.

Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C‐terminal domain phosphatase, Scp1

The phosphoryl‐aspartate intermediate is captured in the crystal structure of a Scp1D206A mutant soaked with para‐nitrophenyl phosphate (pNPP), providing strong evidence for the proposed mechanism and suggesting that Asp206 and its equivalent residues in other HAD family members play important structural and possible mechanistic roles.

The multiple roles of myelin protein genes during the development of the oligodendrocyte

In the present review, the newly emerging functions of these myelin proteins will be described, and these will be discussed in the context of their contribution to oligodendroglial development.