Regulatory T cells reinforce intestinal homeostasis.

@article{Barnes2009RegulatoryTC,
  title={Regulatory T cells reinforce intestinal homeostasis.},
  author={Michael James Barnes and Fiona Powrie},
  journal={Immunity},
  year={2009},
  volume={31 3},
  pages={
          401-11
        }
}
Regulatory T cells help maintain intestinal homeostasis by preventing inappropriate innate and adaptive immune responses. CD4(+) T cells that express Foxp3 and Tr1-like cells that produce IL-10 comprise the major regulatory populations in the intestine. CD4(+)Foxp3(+) T cells play an important functional role in promoting tolerance of the flora and dietary proteins. Tr1-like cells can be generated in conditions that also promote effector T cell responses and may serve a similar function. In… CONTINUE READING
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