Regulatory T cells modulate inflammation and reduce infarct volume in experimental brain ischaemia

Abstract

Brain ischaemia (stroke) triggers an intense inflammatory response predominately mediated by the accumulation of inflammatory cells and mediators in the ischaemic brain. In this context, regulatory T (Treg) cells, a subpopulation of CD4(+) T cells with immunosuppressive and anti-inflammatory properties, are activated in the late stages of the disease. To… (More)
DOI: 10.1111/jcmm.12304

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