Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection.

Abstract

Foxp3(+) regulatory T cells (Tregs) have a well-characterized role in limiting autoimmunity and dampening deleterious immune responses. However, a potential consequence of the immunosuppressive function of Tregs can be the limitation of protective immunity to infectious pathogens. Parasitic infections are a potent stimulus for the generation of Treg… (More)
DOI: 10.4049/jimmunol.1202502

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@article{Sawant2014RegulatoryTC, title={Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection.}, author={Deepali V. Sawant and David M. Gravano and Peter Vogel and Paul R. Giacomin and David A. Artis and Dario Vignali}, journal={Journal of immunology}, year={2014}, volume={192 6}, pages={2904-12} }