Regulatory T cells increased while IL-1β decreased during antidepressant therapy.

  title={Regulatory T cells increased while IL-1β decreased during antidepressant therapy.},
  author={Hubertus Himmerich and Sa{\vs}a Milenovi{\'c} and Stephany Fulda and Birgit Pl{\"u}m{\"a}kers and Abigail J. Sheldrick and Tanja M. Michel and Tilo Kircher and Lothar Rink},
  journal={Journal of psychiatric research},
  volume={44 15},
BACKGROUND Regulatory T cells (Tregs, CD4(+)CD25(hi)) are specialized in steering the immune response and cytokine release to maintain tolerance to self-antigens. As cytokines such as interleukin (IL)-1β, IL-6 and interferon (IFN)-α have been shown to be involved in the pathophysiology of depression and cytokine levels have been shown to change during successful antidepressant treatment, we tested the involvement CD4(+)CD25(hi) Tregs in these immunological processes during antidepressant… CONTINUE READING
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An analytic approximation to the distribution of Lilliefors’ test for normality

  • GE Dallal, L. Wilkinson
  • The American Statistician
  • 1986
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