Regulatory T cells in inflammatory bowel diseases and colorectal cancer.

  title={Regulatory T cells in inflammatory bowel diseases and colorectal cancer.},
  author={Gy{\"o}rgyi Műzes and B{\'e}la Moln{\'a}r and Ferenc Sipos},
  journal={World journal of gastroenterology},
  volume={18 40},
Regulatory T cells (T(regs)) are key elements in immunological self-tolerance. The number of T(regs) may alter in both peripheral blood and in colonic mucosa during pathological circumstances. The local cellular, microbiological and cytokine milieu affect immunophenotype and function of T(regs). Forkhead box P3+ T(regs) function shows altered properties in inflammatory bowel diseases (IBDs). This alteration of T(regs) function can furthermore be observed between Crohn's disease and ulcerative… CONTINUE READING


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