Regulatory T cells in experimental autoimmune disease

@article{SuriPayer2006RegulatoryTC,
  title={Regulatory T cells in experimental autoimmune disease},
  author={Elisabeth Suri‐Payer and Benedikt Fritzsching},
  journal={Springer Seminars in Immunopathology},
  year={2006},
  volume={28},
  pages={3-16}
}
During the past 10 years, CD4+CD25+Foxp3+ regulatory T cells (Treg) have been extensively studied for their function in autoimmune disease. This review summarizes the evidence for a role of Treg in suppression of innate and adaptive immune responses in experimental models of autoimmunity including arthritis, colitis, diabetes, autoimmune encephalomyelitis, lupus, gastritis, oophoritis, prostatitis, and thyroiditis. Antigen-specific activation of Treg, but antigen-independent suppressive… 
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