Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner

@article{Yaqub2007RegulatoryTC,
  title={Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner},
  author={Sheraz Yaqub and Karen Henjum and Milada Mahic and Frode L Jahnsen and Einar Martin Aandahl and Bj\orn Atle Bj\ornbeth and Kjetil Task{\'e}n},
  journal={Cancer Immunology, Immunotherapy},
  year={2007},
  volume={57},
  pages={813-821}
}
Naturally occurring regulatory T (TR) cells suppress autoreactive T cells whereas adaptive TR cells, induced in the periphery, play an important role in chronic viral diseases and cancer. Several studies indicate that cyclooxygenase (COX) inhibitors prevent cancer development of colon adenomas and delay disease progression in patients with colorectal cancer… CONTINUE READING