Regulatory T cells in asthma.

  title={Regulatory T cells in asthma.},
  author={Clare M Lloyd and Catherine M Hawrylowicz},
  volume={31 3},
Asthma is characterized by T helper cell 2 (Th2) type inflammation, leading to airway hyperresponsiveness and tissue remodeling. Th2 cell-driven inflammation is likely to represent an abnormal response to harmless airborne particles. These reactions are normally suppressed by regulatory T cells, which maintain airway tolerance. The anti-inflammatory cytokine IL-10 is likely to play a central role. The role of the cytokine transforming growth factor beta (TGF-beta) is more complex, with evidence… CONTINUE READING

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