Regulatory T cells and transplantation tolerance.

  title={Regulatory T cells and transplantation tolerance.},
  author={Shuiping Jiang and R. Lechler and Xiao-shun He and Jie-fu Huang},
  journal={Human immunology},
  volume={67 10},
In the past decade, several types of regulatory T cells (Tregs) have been identified to play a pivotal role in the control of autoimmunity and transplantation tolerance in rodents and in human beings, including innate regulatory NKT cells and gammadelta T cells, naturally occurring FoxP3 expressing CD4(+)CD25(+) T cells, and in-vitro induced Tregs including interleuking-10 (IL-10)-secreting Tr1 CD4(+) T cells, TGF-beta-producing Th3 CD4(+) T cells, anergic CD4(+) T cells, CD8(+)CD28(-) and CD3… CONTINUE READING

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