Regulatory T cells and mechanisms of immune system control

  title={Regulatory T cells and mechanisms of immune system control},
  author={Anne O'Garra and Paulo Vieira},
  journal={Nature Medicine},
The immune system evolved to protect the host against the attack of foreign, potentially pathogenic, microorganisms. It does so by recognizing antigens expressed by those microorganisms and mounting an immune response against all cells expressing them, with the ultimate aim of their elimination. Various mechanisms have been reported to control and regulate the immune system to prevent or minimize reactivity to self-antigens or an overexuberant response to a pathogen, both of which can result in… CONTINUE READING
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