Regulatory T cells and chronic immune activation in human immunodeficiency virus 1 (HIV-1)-infected children.


The function of CD4(+) T cells with regulatory activity (T(regs)) is the down-regulation of immune responses. This suppressive activity may limit the magnitude of effector responses, resulting in failure to control human immunodeficiency virus 1 (HIV-1) infection, but may also suppress chronic immune activation, a characteristic feature of HIV-1 disease. We… (More)
DOI: 10.1111/j.1365-2249.2011.04383.x


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