Regulatory T Cells in Human Lymphatic Filariasis: Stronger Functional Activity in Microfilaremics

@inproceedings{Wammes2012RegulatoryTC,
  title={Regulatory T Cells in Human Lymphatic Filariasis: Stronger Functional Activity in Microfilaremics},
  author={Linda J Wammes and Firdaus Hamid and Aprilianto Eddy Wiria and H. Wibowo and Erliyani Sartono and Rick M. Maizels and Hermelijn H Smits and Taniawati Supali and Maria Yazdanbakhsh},
  booktitle={PLoS neglected tropical diseases},
  year={2012}
}
Infection with filarial parasites is associated with T cell hyporesponsiveness, which is thought to be partly mediated by their ability to induce regulatory T cells (Tregs) during human infections. This study investigates the functional capacity of Tregs from different groups of filarial patients to suppress filaria-specific immune responses during human filariasis. Microfilaremic (MF), chronic pathology (CP) and uninfected endemic normal (EN) individuals were selected in an area endemic for… CONTINUE READING
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