Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

@article{Woo2001RegulatoryCT,
  title={Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.},
  author={Edward Y. Woo and Christina Seiman Chu and T. Goletz and Katia Schlienger and Hung-I. Yeh and George Coukos and Stephen C. Rubin and Larry Robert Kaiser and Carl H June},
  journal={Cancer research},
  year={2001},
  volume={61 12},
  pages={
          4766-72
        }
}
Immunosuppression may contribute to the progression of cancer. In this study we assessed the structural and functional status of T cells from tumor specimens obtained from patients with early stage non-small cell lung cancer and late-stage ovarian cancer. Although some groups have described structural alterations in the TCR in patients with other malignancies, we did not observe decreased expression of the CD3zeta subunit in the tumor-associated T cells. However, increased percentages of CD4… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 496 CITATIONS

FILTER CITATIONS BY YEAR

2002
2019

CITATION STATISTICS

  • 16 Highly Influenced Citations

  • Averaged 16 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 40 REFERENCES

Similar Papers

Loading similar papers…