Regulatory B cells in autoimmunity: developments and controversies


Over a decade has now passed since the concept of B cells with a regulatory function was resurrected—B cells that produce antibodies with a suppressive effect were first reported in the 1960s and suppressor B cells in the 2000s. In the meantime, some aspects of regulatory B (BREG)-cell biology have been elucidated. Not only have scientists begun to unravel… (More)
DOI: 10.1038/nrrheum.2010.140


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