Regulatory B and T lymphocytes in multiple sclerosis: friends or foes?

@inproceedings{Vasileiadis2018RegulatoryBA,
  title={Regulatory B and T lymphocytes in multiple sclerosis: friends or foes?},
  author={Georgios K. Vasileiadis and Efthymios Dardiotis and Athanasios Mavropoulos and Zisis Tsouris and Vana Tsimourtou and Dimitrios P Bogdanos and Lazaros I Sakkas and Georgios M Hadjigeorgiou},
  booktitle={Autoimmunity Highlights},
  year={2018}
}
Current clinical experience with immunomodulatory agents and monoclonal antibodies in principle has established the benefit of depleting lymphocytic populations in relapsing–remitting multiple sclerosis (RRMS). B and T cells may exert multiple pro-inflammatory actions, but also possess regulatory functions making their role in RRMS pathogenesis much more complex. There is no clear correlation of Tregs and Bregs with clinical features of the disease. Herein, we discuss the emerging data on… CONTINUE READING
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