Regulators of actin filament barbed ends at a glance.

  title={Regulators of actin filament barbed ends at a glance.},
  author={Shashank Shekhar and Julien Pernier and M. Carlier},
  journal={Journal of cell science},
  volume={129 6},
Cells respond to external stimuli by rapidly remodeling their actin cytoskeleton. At the heart of this function lies the intricately controlled regulation of individual filaments. The barbed end of an actin filament is the hotspot for the majority of the biochemical reactions that control filament assembly. Assays performed in bulk solution and with single filaments have enabled characterization of a plethora of barbed-end-regulating proteins. Interestingly, many of these regulators work in… CONTINUE READING
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