Regulators in the apoptotic pathway during spermatogenesis: Killers or guards?

@article{Xu2016RegulatorsIT,
  title={Regulators in the apoptotic pathway during spermatogenesis: Killers or guards?},
  author={Ya-ru Xu and H J Dong and Wan-Xi Yang},
  journal={Gene},
  year={2016},
  volume={582 2},
  pages={
          97-111
        }
}
Apoptosis occurs at any time in the ontogeny of the testis, especially during the first wave of spermatogenesis. However, the exact mechanisms by which homeostasis of apoptosis and survival in GCs and mature sperm are orchestrated remain unclear. Three pathways during the process of apoptosis in mammals are discussed extensively. The three pathways are extrinsic pathway, mitochondrial pathway and endoplasmic reticulum pathway. Based on that, many factors, such as growth factors (SCF, FGF, TGF… CONTINUE READING

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