Regulators encoded in the Escherichia coli type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic E. coli O157:H7.

@article{Zhang2004RegulatorsEI,
  title={Regulators encoded in the Escherichia coli type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic E. coli O157:H7.},
  author={Lihong Zhang and Roy R. Chaudhuri and Chrystala Constantinidou and Jon L. Hobman and Maitray D. Patel and Antony C Jones and D. Sarti and Andrew J Roe and Isabella Vlisidou and Robert K. Shaw and Francesco Falciani and Mark P. Stevens and David L. Gally and Stuart Knutton and Gad Frankel and Charles W. Penn and Mark J. Pallen},
  journal={Infection and immunity},
  year={2004},
  volume={72 12},
  pages={
          7282-93
        }
}
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 subverts host cells through a type III secretion system encoded by the locus for enterocyte effacement (LEE). Genome sequencing of this pathotype revealed the existence of a gene cluster encoding components of a second cryptic type III secretion system, E. coli type III secretion system 2 (ETT2). Recently, we showed that the ETT2 gene cluster is present in whole or in part in the majority of E. coli strains but is unable to encode a functional… CONTINUE READING

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