Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis

@article{Oshiumi2009RegulatorOC,
  title={Regulator of complement activation (RCA) gene cluster in Xenopus tropicalis},
  author={Hiroyuki Oshiumi and Yuzuru Suzuki and Misako Matsumoto and Tsukasa Seya},
  journal={Immunogenetics},
  year={2009},
  volume={61},
  pages={371-384}
}
Genome and expressed sequence tag information of Xenopus tropicalis suggested that short-consensus repeat (SCR)-containing proteins are encoded by three genes that are mapped within a 300-kb downstream of PFKFB2, which is a marker gene for the regulator of complement activation (RCA) loci in human and chicken. Based on this observation, we cloned the three cDNAs of these proteins using 3′- or 5′-RACE technique. Since their primary structures and locations of the proximity to the PFKFB2 locus… CONTINUE READING
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