Regulator of G protein signaling 20 enhances cancer cell aggregation, migration, invasion and adhesion.

@article{Yang2016RegulatorOG,
  title={Regulator of G protein signaling 20 enhances cancer cell aggregation, migration, invasion and adhesion.},
  author={Lei Yang and Maggie M. K. Lee and Manton Man Hon Leung and Y. H. Wong},
  journal={Cellular signalling},
  year={2016},
  volume={28 11},
  pages={
          1663-72
        }
}
Several RGS (regulator of G protein signaling) proteins are known to be upregulated in a variety of tumors but their roles in modulating tumorigenesis remain undefined. Since the expression of RGS20 is elevated in metastatic melanoma and breast tumors, we examined the effects of RGS20 overexpression and knockdown on the cell mobility and adhesive properties of different human cancer cell lines, including cervical cancer HeLa, breast adenocarcinoma MDA-MB-231, and non-small cell lung carcinoma… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 65 REFERENCES

RGS17

M. A. James, Y. Lu, Y. Liu, H. G. Vikis, M. You
  • an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP- PKA-CREB pathway, Cancer Res. 69
  • 2009
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