Regulator of G-Protein Signaling 14 (RGS14) Is a Selective H-Ras Effector

Abstract

BACKGROUND Regulator of G-protein signaling (RGS) proteins have been well-described as accelerators of Galpha-mediated GTP hydrolysis ("GTPase-accelerating proteins" or GAPs). However, RGS proteins with complex domain architectures are now known to regulate much more than Galpha GTPase activity. RGS14 contains tandem Ras-binding domains that have been… (More)
DOI: 10.1371/journal.pone.0004884

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