Regulation of zygotic genome activation and DNA damage checkpoint acquisition at the mid-blastula transition.

Abstract

Following fertilization, oviparous embryos undergo rapid, mostly transcriptionally silent cleavage divisions until the mid-blastula transition (MBT), when large-scale developmental changes occur, including zygotic genome activation (ZGA) and cell cycle remodeling, via lengthening and checkpoint acquisition. Despite their concomitant appearance, whether… (More)
DOI: 10.4161/15384101.2014.967066

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@article{Zhang2014RegulationOZ, title={Regulation of zygotic genome activation and DNA damage checkpoint acquisition at the mid-blastula transition.}, author={Maomao Zhang and Priyanka Kothari and Mary C Mullins and Michael A Lampson}, journal={Cell cycle}, year={2014}, volume={13 24}, pages={3828-38} }