Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.

@article{Kaeberlein2005RegulationOY,
  title={Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients.},
  author={Matt Kaeberlein and R. Wilson Powers and Kristan K. Steffen and Eric A Westman and Di Hu and Nick Dang and Emily O. Kerr and Kathryn T Kirkland and Stanley Fields and Brian K. Kennedy},
  journal={Science},
  year={2005},
  volume={310 5751},
  pages={
          1193-6
        }
}
Calorie restriction increases life span in many organisms, including the budding yeast Saccharomyces cerevisiae. [...] Key ResultsFrom a large-scale analysis of 564 single-gene-deletion strains of yeast, we identified 10 gene deletions that increase replicative life span. Six of these correspond to genes encoding components of the nutrient-responsive TOR and Sch9 pathways. Expand Abstract

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 624 CITATIONS, ESTIMATED 59% COVERAGE

Longevity genomics across species.

  • Current genomics
  • 2007
VIEW 8 EXCERPTS
CITES BACKGROUND

Sir2 and calorie restriction in yeast: A skeptical perspective

  • Ageing Research Reviews
  • 2007
VIEW 8 EXCERPTS
CITES BACKGROUND & RESULTS

FILTER CITATIONS BY YEAR

2004
2020

CITATION STATISTICS

  • 35 Highly Influenced Citations

  • Averaged 31 Citations per year from 2017 through 2019