Regulation of vasopressin synthesis and release by area postrema in rats.

@article{Arima1998RegulationOV,
  title={Regulation of vasopressin synthesis and release by area postrema in rats.},
  author={Hiroshi Arima and Kazunao Kondo and Takashi Murase and Hisashi Yokoi and Yasumasa Iwasaki and Hideya Saito and Yutaka Oiso},
  journal={Endocrinology},
  year={1998},
  volume={139 4},
  pages={1481-6}
}
There is evidence indicating that the area postrema (AP), the most caudal circumventricular organ located on the dorsal surface of the medulla, is involved in several physiological regulations. In this study, we investigated the role of AP in the regulation of arginine vasopressin (AVP) synthesis and release, using rats of which the AP was lesioned 6 weeks previously. The level of plasma AVP in the AP lesioned (APX) group was significantly lower than in the sham operated (Sham) group in the… CONTINUE READING

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