Regulation of valvular interstitial cell calcification by components of the extracellular matrix.

@article{Rodriguez2009RegulationOV,
  title={Regulation of valvular interstitial cell calcification by components of the extracellular matrix.},
  author={Karien J Rodriguez and Kristyn S. Masters},
  journal={Journal of biomedical materials research. Part A},
  year={2009},
  volume={90 4},
  pages={1043-53}
}
Understanding the interactions between extracellular matrix (ECM) components and valvular interstitial cells (VICs) is relevant to both treating heart valve disease and designing heart valve tissue engineering scaffolds, yet the VIC-ECM relationship has not been well characterized. Thus, the aim of this study was to characterize VIC-ECM interactions, paying specific attention to whether ECM composition affected the in vitro calcification of VICs. Our results show that the number and size of… CONTINUE READING

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