Regulation of tumor necrosis factor (TNF) release by murine peritoneal macrophages: role of cell stimulation and specific phagocytic plasma membrane receptors.

@article{Stein1991RegulationOT,
  title={Regulation of tumor necrosis factor (TNF) release by murine peritoneal macrophages: role of cell stimulation and specific phagocytic plasma membrane receptors.},
  author={Monika Stein and Siamon Gordon},
  journal={European journal of immunology},
  year={1991},
  volume={21 2},
  pages={431-7}
}
In spite of the physiologic and pathologic importance of tumor necrosis factor (TNF), the cellular factors that govern its release by macrophages (M phi) are poorly understood, in comparison with other secretory products. We have studied the role of M phi heterogeneity and of plasma membrane receptors in regulating TNF release in vitro. Resident and various exudate murine peritoneal M phi populations were challenged with lipopolysaccharide (LPS) or different phagocytic particles, and TNF… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

In Vivo Cellular Imaging for Translational Medical Research.

Current medical imaging reviews • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…