Regulation of translation initiation by FRAP/mTOR.

@article{Gingras2001RegulationOT,
  title={Regulation of translation initiation by FRAP/mTOR.},
  author={Anne-Claude Gingras and Brian Raught and Nahum Sonenberg},
  journal={Genes \& development},
  year={2001},
  volume={15 7},
  pages={
          807-26
        }
}
Regulation of protein synthesis in eukaryotes plays a critical role in development, differentiation, cell cycle progression, cell growth, and apoptosis (Mathews et al. 2000). Translational control allows for a more rapid response than transcriptional modulation because no mRNA synthesis, processing, or transport is required, and can be used to coordinate gene expression in systems that lack transcriptional regulation, such as reticulocytes or platelets (Weyrich et al. 1998; Mathews et al. 2000… 

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