Regulation of transcriptional elongation by RNA polymerase II.

  title={Regulation of transcriptional elongation by RNA polymerase II.},
  author={David L. Bentley},
  journal={Current opinion in genetics & development},
  volume={5 2},
The process of transcription is a cycle of initiation, elongation and termination steps. Initiation and elongation can be rate-limiting for RNA synthesis, and recent evidence shows that transactivators can stimulate both these steps. A stable modification of the RNA polymerase II complex is probably required to convert it from a non-processive to a processive from. 

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