Regulation of the ventral tegmental area by the bed nucleus of the stria terminalis is required for expression of cocaine preference.

@article{Sartor2012RegulationOT,
  title={Regulation of the ventral tegmental area by the bed nucleus of the stria terminalis is required for expression of cocaine preference.},
  author={G. Crepaldi C. Arnold G. Sartor and Gary S. Aston-Jones},
  journal={The European journal of neuroscience},
  year={2012},
  volume={36 11},
  pages={3549-58}
}
Lateral hypothalamus (LH) orexin neurons are essential for the expression of a cocaine place preference. However, the afferents that regulate the activity of these orexin neurons during reward behaviors are not completely understood. Using tract tracing combined with Fos staining, we examined LH afferents for Fos induction during cocaine preference in rats. We found that the ventral bed nucleus of the stria terminalis (vBNST) was a major input to the LH orexin cell field that was significantly… CONTINUE READING
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