Regulation of the third member of the uncoupling protein family, UCP3, by cold and thyroid hormone.

@article{Larkin1997RegulationOT,
  title={Regulation of the third member of the uncoupling protein family, UCP3, by cold and thyroid hormone.},
  author={Selena Larkin and Eric S Mull and Wenfeng Miao and Richard Pittner and Keith Albrandt and Craig Moore and Anna L. Young and Maria Gabriella Denaro and Kevin Beaumont},
  journal={Biochemical and biophysical research communications},
  year={1997},
  volume={240 1},
  pages={222-7}
}
Uncoupling protein (UCP1) is a transmembrane proton transporter present in the mitochondria of brown adipose tissue (BAT), a specialized tissue which functions in temperature homeostasis and energy balance (Nicholls, D. G., and Locke, R. M. (1984) Physiol. Rev. 64, 2-40; Lowell, D. D., and Flier, J. S. (1997) Annu. Rev. Med.). UCP1 mediates the thermogenesis that is characteristic of BAT by uncoupling mitochondrial oxidation of substrates from ATP synthesis. Recently, two proteins related to… CONTINUE READING

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