Regulation of the tension of human chorionic vasculature by histamine and prostaglandin F2α

  title={Regulation of the tension of human chorionic vasculature by histamine and prostaglandin F2$\alpha$},
  author={Carolyn W. Quist and Robert Chamblet Adams and Eugene E. Quist},
  journal={The Journal of the American Osteopathic Association},
  pages={317 - 326}
The calcium dependence of potassium chloride-, prostaglandin F2 alpha (PGF2 alpha)-, and histamine-induced contractions of human chorionic vasculature segments was investigated. In physiologic buffer that contained 1.5 mM calcium chloride, 60 mM potassium chloride induced a rapid and sustained contraction of the vasculature. Potassium chloride-induced contractions were completely inhibited by the calcium channel blockers diltiazem and nifedipine or by excluding Ca2+ from the medium. Histamine… 



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