Regulation of the synthesis of brain metallothioneins.

Metallothioneins (MTs) area family of low molecular weight proteins characterized by a high cysteine (about 30%) and heavy metal (Zn2+, Cu+) content. In rodents, there are four known MT isoforms, named MT-I to MT-IV. MT-I and MT-II are two widely expressed isoforms, while MT-III and MT-IV (isoforms recently discovered) have a more restricted expression… CONTINUE READING