Corpus ID: 26831032

Regulation of the stress-like protein adenotin in PC 12 cells by ethanol exposure.

@article{Rabin1996RegulationOT,
  title={Regulation of the stress-like protein adenotin in PC 12 cells by ethanol exposure.},
  author={R. Rabin},
  journal={Biochemical pharmacology},
  year={1996},
  volume={51 2},
  pages={
          183-6
        }
}
  • R. Rabin
  • Published 1996
  • Medicine
  • Biochemical pharmacology
The effects of chronic ethanol exposure on the stress-like protein adenotin were investigated using the radioligand [3H]-5'-N-ethylcarboxamidoadenosine ([3H]NECA). A 4-day exposure to 150 mM ethanol increased both the KD and the density of [3H]NECA binding sites. These changes were not due to residual ethanol as the acute addition of ethanol did not alter [3H]NECA binding. Chronic ethanol exposure of A126-1B2-1 cells, which are a mutant PC 12 cell line deficient in protein kinase A (PKA… Expand