Regulation of the stoichiometry of protein components of the stimulatory adenylyl cyclase cascade.

@article{Milligan1997RegulationOT,
  title={Regulation of the stoichiometry of protein components of the stimulatory adenylyl cyclase cascade.},
  author={Graeme Milligan and Ian Mullaney and Gap Don Kim and David J MacEwan},
  journal={Advances in pharmacology},
  year={1997},
  volume={42},
  pages={
          462-5
        }
}
Publisher Summary Rapid progress has been made in methods to transgenically alter levels of signal-transducing polypetides in mice, in a tissue-specific manner in most of the cases. These studies can be invisaged to presage the use of such strategies in human gene therapy, and, thus, it is clearly of vital importance that simpler systems be developed in parallel to allow examination of how transgenic modification of the flux through signal transduction cascades might be modified by regulation… CONTINUE READING
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