Regulation of the retinoblastoma proteins by the human herpesviruses


Viruses are obligate intracellular parasites that alter the environment of infected cells in order to replicate more efficiently. One way viruses achieve this is by modulating cell cycle progression. The main regulators of progression out of G0, through G1, and into S phase are the members of the retinoblastoma (Rb) family of tumor suppressors. Rb proteins… (More)
DOI: 10.1186/1747-1028-4-1