Regulation of the profile of iron-management proteins in brain microvasculature.

@article{Burdo2004RegulationOT,
  title={Regulation of the profile of iron-management proteins in brain microvasculature.},
  author={Joseph R. Burdo and Ian A. Simpson and Sharon Menzies and J. P. Beard and James R. Connor},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2004},
  volume={24 1},
  pages={67-74}
}
The distribution of brain iron is heterogeneous, but the mechanism by which these regional differences are achieved and maintained is unknown. In this study, the authors test two hypotheses related to brain iron transport. The first is that there is regional variability in the profile of proteins associated with iron transport and storage in the brain microvasculature. The second hypothesis is that the iron status of the brain will dictate the response of the protein profile in the… CONTINUE READING

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