Regulation of the production of granulocyte-macrophage colony-stimulating factor by macrophage-like tumour cell lines.

@article{Hume1985RegulationOT,
  title={Regulation of the production of granulocyte-macrophage colony-stimulating factor by macrophage-like tumour cell lines.},
  author={David A. Hume and Kim M. Summers and Donna R Cohen and William Allan},
  journal={FEBS letters},
  year={1985},
  volume={180 2},
  pages={271-4}
}
Macrophage tumour cell lines (PU5-1.8, P388D1) produced detectable granulocyte macrophage colony-stimulating (CSF-2) activity measured using a factor-dependent cell line FDC-P1. The production of CSF-2 was enhanced by endotoxin and inhibited by serum, and correlated inversely with [3H]TdR incorporation. mRNA isolated from PU5-1.8 or P388D1 cells initiated… CONTINUE READING